Serie A September 12 Preview: Venezia vs Fiorentina & Genoa vs Frosinone | Predictions and Score Tips

Serie A Matchday 4 begins with two intriguing fixtures as Venezia host Fiorentina, while Genoa take on newly-promoted Frosinone.

Both matches feature teams under very different kinds of pressure. Fiorentina are hoping for an immediate response after changing managers, while Frosinone arrive in Genoa as one of the early surprise packages of the 2026/27 Serie A season.

Venezia vs Fiorentina: Can Vanoli Spark an Immediate Revival?

Fiorentina's start to the season has been disastrous.

The Viola have lost all three Serie A matches, scoring only one goal and conceding nine. Those results led to Fabio Grosso's dismissal, with Paolo Vanoli returning as head coach.

Interestingly, Vanoli's first match back comes against one of his former clubs. He previously managed Venezia and helped guide them back to Serie A.

Venezia have also started the season with three straight defeats, so this is already an important match for both sides.

The hosts also have defensive concerns. Several centre-backs are dealing with injuries, which could give Fiorentina an opportunity to press higher and attack a back line that may lack chemistry.

Vanoli has had very little time to implement major tactical changes, but the managerial switch could provide Fiorentina with the mental boost they desperately need.

With more individual quality in the squad, the Viola get a narrow edge.

Prediction: Fiorentina to win or draw, with an away win preferred

Score Prediction: Venezia 1-2 Fiorentina

Genoa vs Frosinone: Can the Newly-Promoted Side Continue Their Strong Run?

This is a fascinating contest based on current form.

Genoa have suffered three defeats from their opening three Serie A matches. Daniele De Rossi's side were beaten 4-1 by Como in their latest outing and remain without a point.

Frosinone have produced a completely different start.

After narrowly losing 1-0 to Juventus on Matchday 1, they responded with an impressive 3-0 away victory over Fiorentina, followed by a 3-2 win against Venezia.

That leaves the newly-promoted side on six points from three matches.

One player to watch is Antonio Raimondo, who has scored four goals across Frosinone's last two Serie A matches. His current form gives Massimiliano Alvini's side a genuine attacking threat against a Genoa defence that has struggled early in the campaign.

Genoa have home advantage and will be desperate to avoid a fourth consecutive league defeat, so this may be closer than the table suggests.

Still, current momentum makes it difficult to oppose Frosinone.

Prediction: Frosinone to win or draw

Score Prediction: Genoa 1-1 Frosinone

Final Verdict

Fiorentina's managerial change makes the Venezia clash particularly interesting. Despite their poor start, the Viola still have enough quality to take advantage of Venezia's defensive problems.

In the second fixture, Frosinone are the form team. Genoa's home advantage deserves respect, but the newly-promoted side have already shown they can perform away from home.

Final Score Tips: Venezia 1-2 Fiorentina | Genoa 1-1 Frosinone

Best Picks: Fiorentina double chance | Frosinone double chance